Associate Professor and Assistant Chair HS, AUH Campus
BSc, Biology
MSc, Physiology
PhD, Electrophysiology/Pharmacology
Bio
Google Scholar ProfileEMPLOYMENT HISTORY:
Assistant Professor, Zayed University (August, 2014 - Present), Abu Dhabi, United Arab Emirates.
Adjunct Lecturer, New York Institute of Technology (January, 2008 - January, 2010), Abu Dhabi, United Arab Emirates.
Lecturer, Ajman University of Science and Technology (February, 2000 - September, 2005), Abu Dhabi, United Arab Emirates.
Teaching and Research Assistant, University of Jordan (June, 1996 - June, 1997), Amman, Jordan.
Office
Abu Dhabi - Khalifa City, FF1-1-029
Phone:
+971 2 599 3375
Email:
Lina.AlKury@zu.ac.aeTeaching Areas
Electrophysiology, molecular biology, biochemistry and pharmacology
Research and Professional Activities
My research focuses on the following main areas:
-
Electrophysiological properties and pharmacology of excitable cells in health and disease.
-
Effects of natural plant products on the functional properties of ion channels and receptors.
-
Effects of diabetes on the cardiovascular function.
Research Grants
1. Jan., 2018- Dec., 2019: Research Cluster Grant, Zayed University
Cluster name: Cancer and Natural products
Project name: Evaluation of the anticancer activity of medicinal plants used in UAE traditional medicine.
Principal investigator
2. Jan. 2017- Dec. 2018: Research Incentive Fund, Zayed University.
Project Title: Regional Effects of type 1 and type 2 diabetes on sodium-calcium exchanger (NCX) current in rat ventricular myocytes.
Principal investigator
3. Jan. 2016- Dec. 2017: Research Cluster Grant, ZAyed University
Cluster Name: Diabetes and Cardiovascular Diseases
Project title: Voltage-dependence of Calcium signaling in Rat Ventricular Myocytes from Type-1 Diabetic Hearts.
Principal investigator
Publications
1. Al Kury, L., Mahgoub, M. Howarth, F.C, Oz, M. Natural Negative Allosteric Modulators of 5-HT3 Receptors. Molecules 2018 23(12), 3186; https://doi.org/10.3390/molecules23123186.
2. Talib WH, Al Kury LT. Parthenolide inhibits tumor-promoting effects of nicotine in lung cancer by inducing P53 - dependent apoptosis and inhibiting VEGF expression. Biomed Pharmacother. 2018 Nov;107 1488-1495. doi:10.1016/j.biopha.2018.08.139. PMID: 30257366.
3. Melnyk MI, Dryn DO, Al Kury LT, Zholos AV, Soloviev AI. Liposomal quercetin potentiates maxi-K channel openings in smooth muscles and restores its activity after oxidative stress. J Liposome Res. 2018 Apr 1-8. doi:10.1080/08982104.2018.1458864. PMID: 29671361.
4. Dryn DO, Melnyk MI, Al Kury LT, Prylutskyy YI, Ritter U, Zholos AV. C60 fullerenes disrupt cellular signalling leading to TRPC4 and TRPC6 channels opening by the activation of muscarinic receptors and G-proteins in small intestinal smooth muscles. Cell Signal. 2018 Mar;43 40-46. doi:10.1016/j.cellsig.2017.12.003. PMID: 29242169.
5. Nebrisi EE, Al Kury LT, Yang KS, Jayaprakash P, Howarth FC, Kabbani N, Oz M. Curcumin potentiates the function of human α7-nicotinic acetylcholine receptors expressed in SH-EP1 cells. Neurochem Int. 2018 Mar;114 80-84. doi:10.1016/j.neuint.2017.12.010. PMID: 29341902.
6. Al Kury L, Sydorenko V, Smail MMA, Qureshi MA, Shmygol A, Oz M, Singh J, Howarth FC. Voltage dependence of the Ca2+ transient in endocardial and epicardial myocytes from the left ventricle of Goto-Kakizaki type 2 diabetic rats. Mol Cell Biochem. 2018 Sep;446(1-2) 25-33. doi:10.1007/s11010-018-3269-0. PMID: 29318456.
7. Al Kury L, Smail M, Qureshi MA, Sydorenko V, Shmygol A, Oz M, Singh J, Howarth FC. Calcium Signaling in the Ventricular Myocardium of the Goto-Kakizaki Type 2 Diabetic Rat. J Diabetes Res. 2018;2018 2974304. doi:10.1155/2018/2974304. PMID: 29850600; PMCID: PMC5914098.
8. Smail M, Al Kury L, Qureshi MA, Shmygol A, Oz M, Singh J, Howarth FC. Cell shortening and calcium dynamics in epicardial and endocardial myocytes from the left ventricle of Goto-Kakizaki type 2 diabetic rats. Exp Physiol. 2018 Apr;103(4) 502-511. doi:10.1113/ep086542. PMID: 29363193.
9. Oz M, El Nebrisi EG, Yang KS, Howarth FC, Al Kury LT. Cellular and Molecular Targets of Menthol Actions. Front Pharmacol. 2017;8 472. doi:10.3389/fphar.2017.00472. PMID: 28769802; PMCID: PMC5513973.
10. AlBlooshi, S., Al Kury, L., Malindretos, P. Breast Cancer Awareness Among Zayed University Female Students. Arab Journal of Nutrition and Exercise (AJNE) 2017 2(3)160-169. doi:HTTPS://DOI.ORG/10.18502/AJNE.V2I3.1357.
11. Howarth FC, AlKury L, Smail M, Qureshi MA, Sydorenko V, et al. Effect of Streptozotocin-Induced Type 1 Diabetes Mellitus on Contraction and Calcium Transport in the Rat Heart. JSM Diabetol Manag. 2017 2(1): 1004.
12. Smail MM, Qureshi MA, Shmygol A, Oz M, Singh J, Sydorenko V, Arabi A, Howarth FC, Al Kury L. Regional effects of streptozotocin-induced diabetes on shortening and calcium transport in epicardial and endocardial myocytes from rat left ventricle. Physiol Rep. 2016 Nov;4(22). doi:10.14814/phy2.13034. PMID: 27884956; PMCID: PMC5357996.
13. Yuill KH, Al Kury LT, Howarth FC. Characterization of L-type calcium channel activity in atrioventricular nodal myocytes from rats with streptozotocin-induced Diabetes mellitus. Physiol Rep. 2015 Nov;3(11). doi:10.14814/phy2.12632. PMID: 26603460; PMCID: PMC4673653.
14. Ali RM, Al Kury LT, Yang KH, Qureshi A, Rajesh M, Galadari S, Shuba YM, Howarth FC, Oz M. Effects of cannabidiol on contractions and calcium signaling in rat ventricular myocytes. Cell Calcium. 2015 Apr;57(4) 290-299. doi:10.1016/j.ceca.2015.02.001. PMID: 25711828.
15. Al Kury LT, Voitychuk OI, Yang KH, Thayyullathil FT, Doroshenko P, Ramez AM, Shuba YM, Galadari S, Howarth FC, Oz M. Effects of the endogenous cannabinoid anandamide on voltage-dependent sodium and calcium channels in rat ventricular myocytes. Br J Pharmacol. 2014 Jul;171(14) 3485-3498. doi:10.1111/bph.12734. PMID: 24758718; PMCID: PMC4105935.
16. Al Kury LT, Yang KH, Thayyullathil FT, Rajesh M, Ali RM, Shuba YM, Howarth FC, Galadari S, Oz M. Effects of endogenous cannabinoid anandamide on cardiac Na⁺/Ca²⁺ exchanger. Cell Calcium. 2014 May;55(5) 231-237. doi:10.1016/j.ceca.2014.02.017. PMID: 24674601.
17. Al Kury LT, Voitychuk OI, Ali RM, Galadari S, Yang KH, Howarth FC, Shuba YM, Oz M. Effects of endogenous cannabinoid anandamide on excitation-contraction coupling in rat ventricular myocytes. Cell Calcium. 2014 Feb;55(2) 104-118. doi:10.1016/j.ceca.2013.12.005. PMID: 24472666.
18. Ashoor A, Nordman JC, Veltri D, Yang KH, Al Kury L, Shuba Y, Mahgoub M, Howarth FC, Sadek B, Shehu A, Kabbani N and Oz M. Menthol binding and inhibition of alpha7-nicotinic acetylcholine receptors. PLoS One 2013 8(7):e67674.
19. Ashoor A, Nordman JC, Veltri D, Yang KH, Shuba Y, Al Kury L, Sadek B, Howarth FC, Shehu A, Kabbani N and Oz M. Menthol Inhibits 5-HT3 Receptor-Mediated Currents. J Pharmacol Exp Ther. 2013 347:398-409.
20. Mahgoub M, Keun-Hang SY, Sydorenko V, Ashoor A, Kabbani N, Al Kury L, Sadek B, Howarth CF, Isaev D, Galadari S and Oz M. Effects of cannabidiol on the function of alpha-nicotinic acetylcholine receptors. Eur J Pharmacol. 2013 720(1-3): 310-319.
21. Ashoor A, Lorke D, Nurulain S, Al Kury L, Petroianu G, Yang KH and Oz M. Effects of phenothiazine-class antipsychotics on the function of α7-nicotinic acetylcholine receptors. Eur J Pharmac. 2011 673(1-3):25-32.
22. Howarth FC, Qureshi MA, Hassan Z, Al Kury LT, Isaev D, Parekh K, Yammahi SR, Oz M, Adrian TE, Adeghate E. Changing pattern of gene expression is associated with ventricular myocyte dysfunction and altered mechanisms of Ca2+ signalling in young type 2 Zucker diabetic fatty rat heart. Exp Physiol. 2011 Mar;96(3) 325-337. doi:10.1113/expphysiol.2010.055574. PMID: 21216827.